Nolvadex Profile:
Tamoxifen citrate is a nonsteroidal agent that has demonstrated potent antiestrogenic properties in animal test systems. The anti estrogenic effects may be related to its ability to compete with estrogen for binding sites in target tissues such as breast. Tamoxifen inhibits the induction of rat mammary carcinoma induced by dimethylbenzanthracene (DMBA) and causes the regression of already established DMBA-induced tumors. In this rat model, Tamoxifen appears to exert its anti tumor effects by binding the estrogen receptors.
Nolvadex Dosing:
Use Tamoxifen as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Tamoxifen comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Tamoxifen refilled.
Tamoxifen may be taken by mouth with or without food.
Take Tamoxifen with water or another nonalcoholic liquid.
Swallow this medication whole. Do not break, crush, or chew before swallowing.
Continue to take Tamoxifen even if you feel well. Do not miss any doses. Taking Tamoxifen at the same time each day will help you to remember to take it.
Missed dose of Nolvadex:
Take the forgotten dose of Nolvadex as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.
Storage – To store Nolvadex:

Keep out of the reach of children.
Store away from heat and direct light.
Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Nolvadex Side effects:
Get emergency medical help if you have any of these signs of an allergic reaction:
Hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using tamoxifen and call your doctor at once if you have any of these serious side effects:
Sudden numbness or weakness, especially on one side of the body; sudden headache, confusion, problems with vision, speech, or balance; chest pain, shortness of breath, or coughing up blood; pain or swelling in one or both legs; unusual vaginal bleeding or discharge; irregular menstrual periods; pain or pressure in your pelvic area; fever, chills, body aches, flu symptoms; pale skin, easy bruising or bleeding; new breast lumps; or nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
Hot flashes, warmth or tingly feeling under your skin; bone, joint, or tumor pain; redness or skin changes; swelling in your hands or feet; vaginal itching or dryness; depressed mood, weakness; weight loss; nausea; cough, sore throat; decreased sex drive, impotence, or difficulty having an orgasm; headache, dizziness; or thinning hair.

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