Essentiale – Essential Phospholipids profile:
Essentiale is a preparation of essential Phospholipids. Essentiale normalizes the metabolism of lipids and proteins, improves the detoxification function of the liver, restores the cellular structure of the liver and retards the producing of conjunctive tissue. Essentiale medications are indicated for the treatment of fatty degeneration of the liver, hepatitis (including toxic hepatitis, liver damage caused by medicines or alcohol abuse), cirrhosis of the liver, disturbances in liver function associated with different illnesses.
Phospholipids are essential structural components of all cellular membranes. Essential phospholipids (substance EPL) – are the complex substances of natural origin (ethers of cholinephosphoric acid (phosphatidylcholine) and unsaturated fatty acids (linoleic, linolenic, olein)). Essentiale medications possess the membranotropic properties, metabolic and hepatoprotective action; regulates lipid and carbohydrate metabolism. Essential phospholipids increase functional status of the liver.
While the disturbance of the liver metabolism essential phospholipids ensure the entering the high energy phospholipids, which are ideally combined with the endogenous phospholipids. Under the Essentialle phospholipids influence clinical and biochemical liver indexes are improved.
Combination of Essentiale with cordiamin (nikethamide) and vitamin E (50 mg/kg for 35 days) considerably activates the mono-oxigenase, glucoro- and glutathione transferase systems of the liver: and as a result the free-radical processes became less intense.
The spectrum of essential Phospholipids activity in chronic degenerative liver diseases can be described in the following properties:

Recovery and maintaining the consistency of the hepatocytes
Activation of the phospholipid-depending ferments
Improvement in the lipids metabolism caused by accelerated synthesis of lipoproteins in the liver
Activation of synthesis RNA and as a result the normalization of the proteins metabolism
Increased synthesis of glycogen in the liver
Improvement in the detoxification function of the liver
The conversion of neutral fats and cholesterol into the easily metabolizing forms
Decreased the fatty infiltration of the hepatocytes

Essentiale is used to treat the following diseases:

Hepatitis (acute and chronic), toxic hepatitis, medicinal and alcoholic hepatitis, poisonings. Hepatic steatosis of different aetiology (in 53.6 % of patients the effect of six-month treatment with Essentiale forte was very good (improvement of all investigated parameters))
Diabetes (the data suggests that Essentiale protects and improves liver function in diabetic subjects with non alcoholic fatty liver and chronic infections)
Disturbance in liver function in somatic diseases
Hepatic cirrhosis
Necrosis of the liver cells, liver failure, liver coma
Presurgical and Postsurgical treatment, especially in hepatobiliary area
Hyperlipoproteinemia, hypercholesterolemia, hypertriglyceridemia
Diseases of the cardiovascular system: coronary heart disease, stable stenocardia, post-infarction condition, disturbance of the cerebral and peripheral circulation, Hypertension, thrombembolia prophylaxis, atherosclerosis, diabetic angiopathy, thrombembolia prophylaxis and fat embolism(solution for injection)
Digestive system diseases (chronic pancreatitis, gastric and duodenum ulcer)
Toxicosis of pregnancy (edema, proteinuria и and blood pressure disorders)
Radiation sickness (radiation syndrome)
Psoriasis, atomic dermatitis, eczema
Prophylaxis of micromegaly

Essentiale dosage:
The dose of Essentiale will be different for different patients. Follow your doctors orders or the directions on the label. The following information includes only the average doses of Essentiale. If your dose is different, do not change it unless your doctor tells you to do so.
The number of capsules that you take depends on the strength of the medicine.
Average dose for the primary dose is 2 capsules 3 times daily.
Storage – To store Essentiale:

Keep out of the reach of children.
Store away from heat and direct light.
Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
Keep the medicine from freezing. Do not refrigerate.
Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Essentiale Side effects:
All medicines may cause side effects, but many people have no, or minor, side effects.
In very rare cases Essentiale can cause:
Abdominal pain, nausea, diarrhea and allergic reaction(skin rash).
Essentiale contradictions and cautions:
Do not use Essentiale in hypersensitivity or allergy to any ingredients of the preparation. The application of Essentiale in newborn children is not safe. During pregnancy women are recommended to consult their health care provider prior to taking Essentiale.

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